Interest in psychedelic drugs has sparked Netflix’s release of How To Change Your Mind: the latest docuseries exploring the history and research on psychedelics, including LSD, psilocybin, MDMA and mescaline. As psychedelics enter the mainstream, becoming increasingly available legally, WeedTube is proud to offer a platform for people to share their experiences and gather information about utilizing psychedelic treatment, without the risk of censorship or deletion.
Studies of psilocybin mushrooms, MDMA, ketamine, and other psychedelics have consistently shown tremendous potential for therapeutic applications. Seemingly every other week a landmark study is released and another cover story in a major publication is printed, demonstrating how these molecules help people.
In increasing numbers, people are turning to psychedelics to overcome anxiety, treatment-resistant depression, eating disorders, stress disorders and smoking cessation. Additionally, this breakthrough therapy can increase creativity, joy, and general wellbeing. In contrast to the pharmaceuticals presently filling that role, psychedelic-assisted therapy uses organic, non-toxic, non-addictive compounds.
Lysergic acid diethylamide (LSD), is a potent synthetic hallucinogenic drug that can be derived from a fungus called ergot alkaloids. LSD is usually prepared by chemical synthesis in a laboratory. LSD produces marked deviations from normal behavior, probably the consequence of its ability to inhibit the action of serotonin, though the mechanism of the drug remains uncertain. Its effects usually last for 8 to 10 hours, and occasionally some effects persist for several days. Two serious side effects are the prolongation and transient reappearance of the psychotic reaction.
LSD and psilocybin are very different but have some similarities and often get compared. Psilocybin is a hallucinogenic compound that occurs in certain types of mushrooms, including the two Mexican species Psilocybe mexicana and P. cubensis. Often referred to as "magic mushrooms", side effects include nausea and vomiting. Recent research on psilocybin-assisted therapy reduces anxiety and depression in patients.
Methylenedioxymethamphetamine (MDMA), is a derivative of amphetamine and a synthetic drug that acts as a stimulant and hallucinogen. It produces an energizing effect, distortions in time and perception, and enhanced enjoyment from sensory experiences. It has also been described as an entactogen—a drug that can increase self-awareness and empathy; which is crucial characteristic to the efficacy of mdma-assisted psychotherapy.
‘Ecstasy’ is often used to refer to MDMA in the tablet or capsule form, which is the most common way people take the drug. CAUTION: Emerging research shows that many ecstasy tablets contain not only MDMA at different concentrations, but also a number of other drugs or drug combinations that can be harmful. Adulterants found in ecstasy tablets purchased on the street have included methamphetamine, the anesthetic ketamine, caffeine, the over-the-counter cough suppressant dextromethorphan, heroin, phencyclidine (PCP), and cocaine. Medical supervision is crucial to ensure the safety of mdma-assisted therapy.
A naturally occurring compound in the flowering heads of the peyote cactus of Mexico and the southwestern United States, Mescaline has been frequently used as a drug to induce hallucination. Clinical trials show that mescaline requires 2-3 hours for onset of action, and the psychedelic effects sometimes last for more than 12 hours. The hallucinatory effects vary greatly among individuals, even for an individual from one session to the next. The variations seem to reflect such factors as the mood and personality of the subject and the setting in which the drug is administered. Hallucinations are usually visual, less often auditory. Side effects include nausea and vomiting.
Ketamine is a general anesthetic agent originally patented in Belgium in 1963, then approved for use in humans by the U.S. Food and Drug Administration in 1970. Soon after, it was put to use to treat American soldiers fighting in the Vietnam War. Today, the drug has been proven to have valuable applications in human medicine, used to treat depression and chronic pain.
The drug is known particularly for its ability to induce a dissociative state, which is characterized by a lack of pain sensation and unconsciousness, which has sparked renewed clinical research to use ketamine therapy for severe PTSD.
While psychedelic therapy remains taboo in today's society, early research suggests that the ancient Greeks used psychedelics under the guise of alcohol use in a beverage called Kykeon, which had similar effects to LSD. Native American and other indigenous populations used different psychedelic drugs also, having illustrated rock paintings of mushrooms portrayed as deities dating back to 7,000 BC.
Psychiatric research of psychedelic medications didn't begin until the 20th Century, when Swiss scientist Albert Hoffman created LSD in attempt to duplicate classic psychedelics found in nature. By the 1950s, LSD became a commonly used psychiatric treatment for a variety of conditions, including alcoholism, schizophrenia and other personality disorders.
Throughout the 1960s, psychedelics were used in clinical studies but took off in popularity with the widespread use among the hippie counterculture, with LSD becoming the most popular of all.
Psychedelic use became a symbol of rebellion, mind exploration and political dissent across the US. This widespread use of LSD soon caught the attention of the US government, so much so that it was made an illegal substance in 1967 and prompted the founding of the National Institute on Drug Abuse in 1974.
The War on Drugs drastically slowed the progress of the research community in discovering the efficacy of using psychedelic drugs to treat common conditions like post-traumatic stress disorder, depression and anxiety. Academic research institutions like Johns Hopkins Center for Psychedelic Drug Research and the Multidisciplinary Association for Psychedelic Studies (MAPS) have given credibility and validity to studies on psychedelic science.
Today, more and more people are integrating small doses of psychedelic substances into their therapy sessions to reach mental breakthroughs that traditional talk therapy might take years to reach. Group therapy sessions are becoming more prevalent with certain psychedelics like ayahuasca, reminiscent of ancient spiritual ceremonies.
While the legality of each psychedelic substance we’ve discussed varies by state, there are potential resources available to access this form of therapy depending on where you live.
At-home therapy treatment delivery services like Field Trip and Mindbloom offer immersive ketamine-assisted psychotherapy programs to support your emotional health and personal growth. If you’re looking for a local provider or in-office ketamine treatments, you can visit the thread r/TherapeuticKetamine on Reddit to find providers all over the US and learn from other patients’ psychedelic experiences.
While Psilocybin still remains widely-illegal under the Controlled Substances Act, there are areas of the country with decriminalized mushrooms for mental health conditions like depression. While Oregon has legalized the use of psychedelic drugs throughout the state, cities like Oakland, CA, Denver, CO, Ann Arbor, MI and Washington, DC have decriminalized psilocybin.
Always understand your local laws pertaining to a particular psychedelic before seeking psychedelic-assisted treatment.
Have more questions about the effects of psychedelics? Check out the playlist below!
In this video, WeedTuber LowkeyFish explains Terence McKenna's "Stoned Ape Theory". This infamous theory is backed by famous philosopher Nick Bostrom, Joe Rogan, Paul Stamets and more. Watch & learn why Psilocybin Mushrooms played a major role in the Evolution of Human Consciousness over the course of 2 million years!
This video from DailyDose shares a case study of participants who underwent psilocybin therapy and MDMA therapy for anxiety or depression. The study shares a wide range of data sets regarding efficacy of these therapies and has prompted law makers to reconsider legal classification with a term being used "right to try", this gives many people the opportunity to experiment with psychedelics to help treat their depression!
Wanna just sesh and see what people act like on mushrooms? Then check out this vlog from DopeAsYola, and check out his channel for more mushroom content!
Check out this panel from Seattle's 2020 Hempfest that brought together scientific experts to discuss using cannabis and psychedelics to support your mental health.
At WeedTube, we're 100% committed to honesty and transparency. And here's a truth: the approach to psychedelic treatment should be done with the utmost caution and care. These substances drastically impact your psyche and utilizing them should be carefully dosed in a safe setting. In this video, WeedTube co-founder Arend Richard details a life-changing experience with psilocybin, not to scare you but to INFORM.
LowkeyFish explains what a K-Hole is, talks to a real scientist about the dangers of Ketamine, debunks corporate misinformation, explains the effects of a Ketamine trip, goes over harm reduction, pharmacology, and personal experiences with Ketamine!
Have you experienced psychedelic therapy's benefits or side effects?
Tell us in the comments below!
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